1. Introduction: Why Aspartame Stirs Debate

Aspartame has been the subject of heated debate for decades—embraced as a low-calorie sweetener in thousands of foods and drinks, yet scrutinized for possible health effects and cancer risks. In 2023, the International Agency for Research on Cancer (IARC) classified aspartame as “possibly carcinogenic to humans” (Group 2B), citing limited evidence for liver cancer in humans, but major global regulatory agencies still affirm its safety at approved intake levels.​

2. The Science: Health, Risks, and Regulatory Reviews

Multiple reviews by the US FDA, EFSA (Europe), JECFA (WHO/FAO), and Health Canada affirm aspartame’s safety when consumed within legal Acceptable Daily Intake (ADI) limits—40 mg/kg body weight. The IARC’s classification is based on limited animal and human data, but the Joint FAO/WHO Expert Committee (JECFA) and EFSA state that “evidence of an association between aspartame consumption and cancer in humans is not convincing” and reaffirmed aspartame’s current safety profile. Consumers would have to ingest far more than typical daily amounts to reach the ADI—e.g., about 9–14 cans of diet soda per day for an average adult.​
However, ongoing concerns in scientific literature highlight the need for new long-term studies on the possible systemic effects of aspartame, especially in at-risk and high-exposure populations.​

3. How Much Is Safe? Regulatory Limits and Market Trends

4. Aspartame in the Global Market: Growth and Challenges

The global aspartame market is projected to grow at 3.5–4.7% CAGR through 2029, reaching more than $475 million in annual sales. Asia-Pacific leads supply and demand as regulatory acceptance rises, while Europe’s strong policy push for low-calorie ingredients supports ongoing growth. However, the industry faces challenges from public skepticism, “aspartame-free” claims by competitors, and continued regulatory scrutiny, driving ongoing innovation and greater transparency.​

5. Conclusion: Making Evidence-Based Choices

Aspartame remains one of the most studied food additives worldwide—approved and reaffirmed safe when used as directed. While regulatory reviews highlight areas for further research, the current consensus allows buyers, manufacturers, and consumers to make informed, science-based decisions in a landscape of evolving food ingredient choices.​