Brief Overview
2,6-Lutidine is a natural heterocyclic aromatic organic compound and has the formula
(CH 3 ) 2 C 5 H 3 N. It is one of several dimethyl-substituted derivative of pyridine. It appears as a
colorless liquid with mildly basic properties and a pungent odor. Though pyridine is source
of carbon, nitrogen, and energy for certain microorganisms, methylation significantly
retards degradation of the pyridine ring. 2,6-Lutidine was found to be significantly more
resistant to microbiological degradation than any of the picoline isomers or 2,4-lutidine in
soil. Significant volatilization loss was observed in liquid media. Estimated time for complete
degradation was > 30 days.
Manufacturing Process
2,6-Lutidine is produced industrially by the reaction of formaldehyde, acetaldehyde,
and ammonia, isolated from basic fraction of coal tar
Food Industry
2,6-Lutidine has been evaluated for use as a food additive due to its nutty aroma when
present in solution at very low concentrations
Pharmaceutical Industry
In Pharmaceutical industry, it can be used for the production of antiatherosclerotic
pyridinolcarbamate.
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